The answer to your problem depends on what type of activity this network application is trying to perform on your local workstations. Once you know that, you can adjust the read/write permissions on the local machine to allow your users access to that directory. If you're getting a specific error message that outlines what directory the application is trying to access, you've got your work cut out for you. If not, you could call the...
software vendor directly and ask them what their software is trying to access or use SysInternals' free FileMon utility to monitor the application.
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