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Can I block a Power Toys program from running on Windows 2000?

Can I completely block the Power Toys program "QuickRes" from running on Windows 2000?
If the tool has already been installed, block it by setting NTFS file permissions. This will prevent it from running. However, the tool might be reinstalled and placed in another folder and then it would run. As long as a user can write to a folder, he can install software of some types.

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